Ingredient database
Acne ingredient database
Every ingredient our conflict checker recognizes, from benzoyl peroxide to fatty alcohols: what it does, whether it's an acne drug, prescription-only or cosmetic, and why it might be flagged.
146 ingredients 6 OTC acne actives 10 prescription
The database has 146 entries, including 6 over-the-counter acne drug actives and 10 prescription acne medicines. Over-the-counter acne actives follow the FDA's acne monograph (M006): benzoyl peroxide 2.5% to 10%, salicylic acid 0.5% to 2%, sulfur 3% to 10%, and sulfur combined with resorcinol. Adapalene 0.1% gel is sold over the counter through a separate FDA drug approval, not the monograph. Everything else here is a cosmetic ingredient, which can't legally be sold as an acne treatment on its own.
27 ingredients carry a “pore-clogging” (comedogenic) note. Treat those as weak hints: most ratings come from decades-old rabbit-ear tests of undiluted ingredients, and a finished product can behave very differently. Our checker page explains how much to trust them.
Browse all ingredients by type
Every ingredient the checker recognizes, with what it does and why it might be flagged. Open a category to see its ingredients. The database has 146 entries and was last checked 2026-09-23.
OTC acne drug active (6)
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Adapalene · also listed as adapalene, differin
A retinoid that helps unclog pores and calm inflammation. Adapalene 0.1% gel became available over the counter in 2016 through an FDA new-drug approval (an Rx-to-OTC switch), not through the acne monograph. Higher strengths need a prescription. Retinoids are generally avoided in pregnancy.
OTC acne drug (FDA new-drug approval) · OTC at 0.1% via FDA new-drug approval (Rx-to-OTC switch); higher strengths Rx
Sources: U.S. Food and Drug Administration (2016) : Approval letter: Differin Gel (adapalene) 0.1% for over-the-counter use, NDA 020380/S-010 (opens in a new tab) ; DailyMed, U.S. National Library of Medicine : DIFFERIN (adapalene) gel 0.1%: over-the-counter Drug Facts label (opens in a new tab) ; Journal of the American Academy of Dermatology (2024) : Guidelines of care for the management of acne vulgaris (Reynolds et al.) (opens in a new tab)
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Benzoyl peroxide · also listed as benzoyl peroxide, bpo, benzoylperoxide, hydrous benzoyl peroxide, …
An OTC acne drug that reduces acne-causing bacteria. The FDA acne monograph allows 2.5% to 10%. It can bleach hair, towels and fabric, and it is irritating for some people, so many dermatologists suggest starting at 2.5%.
OTC acne drug (FDA monograph M006) · OTC acne drug (FDA monograph M006), 2.5–10%
Sources: U.S. Food and Drug Administration (2021) : OTC Monograph M006: Topical Acne Drug Products for Over-the-Counter Human Use (opens in a new tab) ; Journal of the American Academy of Dermatology (2024) : Guidelines of care for the management of acne vulgaris (Reynolds et al.) (opens in a new tab) ; American Academy of Dermatology : 10 tips for clearing acne in darker skin tones (opens in a new tab)
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Resorcinol · also listed as resorcinol
Allowed in OTC acne products only in combination with sulfur (resorcinol 2% with sulfur 3–8%). It is not approved as a single acne active.
OTC acne drug (FDA monograph M006) · OTC acne drug only with sulfur (FDA monograph M006)
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Resorcinol monoacetate · also listed as resorcinol monoacetate
Allowed in OTC acne products only in combination with sulfur (resorcinol monoacetate 3% with sulfur 3–8%).
OTC acne drug (FDA monograph M006) · OTC acne drug only with sulfur (FDA monograph M006)
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Salicylic acid · also listed as salicylic acid, bha, beta hydroxy acid, beta-hydroxy acid, …
A beta hydroxy acid (BHA) that helps clear clogged pores. As an OTC acne drug the FDA monograph allows 0.5% to 2%; it also appears in cosmetics as an exfoliant. The 2024 AAD guideline gives it a conditional recommendation. Ask a clinician before using it in pregnancy.
OTC acne drug (FDA monograph M006) · OTC acne drug (FDA monograph M006), 0.5–2%
Sources: U.S. Food and Drug Administration (2021) : OTC Monograph M006: Topical Acne Drug Products for Over-the-Counter Human Use (opens in a new tab) ; Journal of the American Academy of Dermatology (2024) : Guidelines of care for the management of acne vulgaris (Reynolds et al.) (opens in a new tab) ; Cochrane Database of Systematic Reviews (2020) : Topical azelaic acid, salicylic acid, nicotinamide, sulphur, zinc and fruit acid (alpha-hydroxy acid) for acne (opens in a new tab)
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Sulfur · also listed as sulfur, sulphur, colloidal sulfur, precipitated sulfur
An older OTC acne drug allowed at 3% to 10% by the FDA monograph, alone or paired with resorcinol. The evidence base is small, and a 2020 Cochrane review was uncertain about its effect. It has a distinctive smell and can be drying.
OTC acne drug (FDA monograph M006) · OTC acne drug (FDA monograph M006), 3–10%
Sources: U.S. Food and Drug Administration (2021) : OTC Monograph M006: Topical Acne Drug Products for Over-the-Counter Human Use (opens in a new tab) ; Cochrane Database of Systematic Reviews (2020) : Topical azelaic acid, salicylic acid, nicotinamide, sulphur, zinc and fruit acid (alpha-hydroxy acid) for acne (opens in a new tab)
Prescription acne medicine (10)
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Azelaic acid · also listed as azelaic acid, azelaic, potassium azeloyl diglycinate
An acid with antibacterial, anti-inflammatory and pore-clearing effects. Azelaic acid 20% cream is a prescription acne treatment; 15% gel and foam are prescription rosacea treatments; lower strengths appear in cosmetics. The 2024 AAD guideline gives it a conditional recommendation.
Prescription acne treatment · 20% cream (acne) and 15% gel (rosacea) are prescription; lower-strength cosmetics exist
Sources: U.S. Food and Drug Administration (2024) : AZELEX (azelaic acid cream) 20%: prescribing information (opens in a new tab) ; Journal of the American Academy of Dermatology (2024) : Guidelines of care for the management of acne vulgaris (Reynolds et al.) (opens in a new tab) ; Cochrane Database of Systematic Reviews (2020) : Topical azelaic acid, salicylic acid, nicotinamide, sulphur, zinc and fruit acid (alpha-hydroxy acid) for acne (opens in a new tab)
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Clascoterone · also listed as clascoterone, winlevi
A prescription topical androgen-receptor blocker for acne. The 2024 AAD guideline gives it a conditional recommendation. We have no specific interaction rules for it; ask your prescriber how to fit it into your routine.
Prescription acne treatment · Prescription only
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Clindamycin · also listed as clindamycin, clindamycin phosphate, clindamycin hydrochloride
A prescription topical antibiotic. The 2024 AAD guideline recommends against using topical antibiotics alone because of resistance, and favors pairing them with benzoyl peroxide.
Prescription acne treatment · Prescription only
Sources: Journal of the American Academy of Dermatology (2024) : Guidelines of care for the management of acne vulgaris (Reynolds et al.) (opens in a new tab) ; The Journal of Dermatology (2026) : Combination effects of clindamycin and benzoyl peroxide against Cutibacterium acnes (opens in a new tab)
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Dapsone (topical) · also listed as dapsone, aczone
A prescription anti-inflammatory gel for acne. Its label warns that using it with benzoyl peroxide can temporarily turn skin or facial hair yellow or orange.
Prescription acne treatment · Prescription only
Sources: U.S. Food and Drug Administration (2019) : ACZONE (dapsone) gel 7.5%: prescribing information (opens in a new tab) ; Journal of the American Academy of Dermatology (2024) : Guidelines of care for the management of acne vulgaris (Reynolds et al.) (opens in a new tab)
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Erythromycin · also listed as erythromycin
A prescription topical antibiotic, sometimes combined with benzoyl peroxide. As with clindamycin, guidelines advise against using it on its own because of antibiotic resistance.
Prescription acne treatment · Prescription only
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Minocycline (topical) · also listed as minocycline, minocycline hydrochloride
A prescription antibiotic available as a topical foam or gel for acne, in addition to the more familiar oral form.
Prescription acne treatment · Prescription only
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Sodium sulfacetamide · also listed as sodium sulfacetamide, sulfacetamide sodium, sulfacetamide
A prescription topical antibiotic often combined with sulfur in washes and creams. Tell your prescriber about any sulfa (sulfonamide) allergy.
Prescription acne treatment · Prescription only
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Tazarotene · also listed as tazarotene, tazorac, arazlo
A prescription retinoid used for acne and psoriasis. It is contraindicated in pregnancy. It tends to be one of the more irritating retinoids.
Prescription acne treatment · Prescription only
Sources: Journal of the American Academy of Dermatology (2024) : Guidelines of care for the management of acne vulgaris (Reynolds et al.) (opens in a new tab) ; Journal of Clinical and Aesthetic Dermatology (2020) : Use of topical tazarotene for the treatment of acne vulgaris in pregnancy: a literature review (opens in a new tab)
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Tretinoin · also listed as tretinoin, retinoic acid, all-trans retinoic acid, all trans retinoic acid, …
A prescription retinoid (retinoic acid) and one of the most studied acne treatments. Standard tretinoin breaks down with light and with benzoyl peroxide, so timing matters. Retinoids are generally avoided in pregnancy.
Prescription acne treatment · Prescription only
Sources: Journal of the American Academy of Dermatology (2024) : Guidelines of care for the management of acne vulgaris (Reynolds et al.) (opens in a new tab) ; DailyMed, U.S. National Library of Medicine : RETIN-A (tretinoin) cream and gel: label (opens in a new tab) ; British Journal of Dermatology (1998) : Chemical stability of adapalene and tretinoin when combined with benzoyl peroxide in presence and in absence of visible light and ultraviolet radiation (opens in a new tab)
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Trifarotene · also listed as trifarotene, aklief
A newer prescription retinoid approved for acne on the face and trunk. Like other retinoids, it is generally avoided in pregnancy.
Prescription acne treatment · Prescription only
Cosmetic retinoid (6)
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Hydroxypinacolone retinoate · also listed as hydroxypinacolone retinoate, hpr, granactive retinoid
A cosmetic retinoid ester often marketed as "granactive retinoid". Published independent evidence is limited; we treat it like other cosmetic retinoids for layering purposes.
No specific acne role
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Retinal (retinaldehyde) · also listed as retinal, retinaldehyde
A cosmetic retinoid one conversion step closer to retinoic acid than retinol. Evidence is mostly for signs of aging rather than acne.
Some evidence in acne, limited
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Retinol · also listed as retinol, vitamin a, encapsulated retinol, retinol (encapsulated)
A cosmetic form of vitamin A that skin converts toward retinoic acid. It is generally gentler and less potent than prescription retinoids. It is sold mainly for signs of aging; the evidence for it as an acne treatment is much thinner than for adapalene or tretinoin.
Some evidence in acne, limited
Sources: Journal of Investigative Dermatology (1995) : Application of retinol to human skin in vivo induces epidermal hyperplasia and cellular retinoid binding proteins characteristic of retinoic acid but without measurable retinoic acid levels or irritation (opens in a new tab) ; Aesthetic Surgery Journal (2010) : Cosmeceuticals: the evidence behind the retinoids (opens in a new tab) ; American Academy of Dermatology : Retinoid or retinol? (opens in a new tab)
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Retinyl acetate · also listed as retinyl acetate, vitamin a acetate
A vitamin A ester used in cosmetics. Like retinyl palmitate, it is a mild, indirect source of retinoid activity.
No specific acne role
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Retinyl palmitate · also listed as retinyl palmitate, vitamin a palmitate
A vitamin A ester and the mildest common cosmetic retinoid. It needs several conversion steps in the skin, so its effect is weaker than retinol.
No specific acne role
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Retinyl propionate · also listed as retinyl propionate
A vitamin A ester used in cosmetic "retinoid" products. Evidence in acne is limited.
No specific acne role
Exfoliating acid (7)
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Betaine salicylate · also listed as betaine salicylate
A salicylic acid derivative used in cosmetics as a milder BHA. It is not an OTC acne drug active.
No specific acne role
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Capryloyl salicylic acid (LHA) · also listed as capryloyl salicylic acid, lha, lipohydroxy acid
A fat-soluble salicylic acid derivative ("LHA") used as a cosmetic exfoliant. It is not an OTC acne drug active.
No specific acne role
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Gluconolactone · also listed as gluconolactone, pha, polyhydroxy acid
A polyhydroxy acid (PHA), a larger and generally gentler relative of AHAs.
No specific acne role
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Glycolic acid · also listed as glycolic acid, aha, alpha hydroxy acid, alpha-hydroxy acid, …
The most common alpha hydroxy acid (AHA). It loosens dead skin cells on the surface. The FDA advises sun protection while using AHA products and for a week after. A 2020 Cochrane review found only low-certainty evidence for AHAs in acne.
Some evidence in acne, limited
Sources: U.S. Food and Drug Administration : Alpha hydroxy acids (cosmetic ingredients) (opens in a new tab) ; Clinical, Cosmetic and Investigational Dermatology (2010) : Applications of hydroxy acids: classification, mechanisms, and photoactivity (opens in a new tab) ; Cochrane Database of Systematic Reviews (2020) : Topical azelaic acid, salicylic acid, nicotinamide, sulphur, zinc and fruit acid (alpha-hydroxy acid) for acne (opens in a new tab)
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Lactic acid · also listed as lactic acid, sodium lactate, ammonium lactate
An AHA that is often described as gentler than glycolic acid. In small amounts it is also used as a pH adjuster, and an ingredient list cannot tell you which role it plays.
No specific acne role
Sources: U.S. Food and Drug Administration : Alpha hydroxy acids (cosmetic ingredients) (opens in a new tab) ; Clinical, Cosmetic and Investigational Dermatology (2010) : Applications of hydroxy acids: classification, mechanisms, and photoactivity (opens in a new tab)
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Lactobionic acid · also listed as lactobionic acid
A bionic acid (a type of PHA) used as a gentle exfoliant and humectant.
No specific acne role
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Mandelic acid · also listed as mandelic acid
A larger-molecule AHA often marketed for sensitive or acne-prone skin. Clinical evidence in acne is limited.
No specific acne role
Sources: Clinical, Cosmetic and Investigational Dermatology (2010) : Applications of hydroxy acids: classification, mechanisms, and photoactivity (opens in a new tab) ; Cochrane Database of Systematic Reviews (2020) : Topical azelaic acid, salicylic acid, nicotinamide, sulphur, zinc and fruit acid (alpha-hydroxy acid) for acne (opens in a new tab)
pH adjuster (3)
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Citric acid · also listed as citric acid, sodium citrate, trisodium citrate
Technically an AHA, but in most products it appears in tiny amounts to adjust pH. We do not treat it as an exfoliant unless a product is clearly marketed as a citric-acid peel.
No specific acne role
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Malic acid · also listed as malic acid
An AHA that is usually present in small amounts as a pH adjuster or in fruit extracts.
No specific acne role
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Tartaric acid · also listed as tartaric acid
An AHA usually present in small amounts, often from fruit extracts or as a pH adjuster.
No specific acne role
Vitamin C and antioxidants (10)
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Ascorbyl glucoside · also listed as ascorbyl glucoside
A stable, water-soluble vitamin C derivative.
No specific acne role
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Ascorbyl palmitate · also listed as ascorbyl palmitate
An oil-soluble vitamin C ester, often used as an antioxidant to protect the formula itself.
No specific acne role
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Ethyl ascorbic acid · also listed as ethyl ascorbic acid, 3-o-ethyl ascorbic acid, 3 o ethyl ascorbic acid
A vitamin C derivative (3-O-ethyl ascorbic acid) used for stability.
No specific acne role
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Ferulic acid · also listed as ferulic acid
A plant antioxidant often paired with vitamins C and E in serums.
No specific acne role
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Magnesium ascorbyl phosphate · also listed as magnesium ascorbyl phosphate, map
A stable vitamin C derivative used in cosmetics.
No specific acne role
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Resveratrol · also listed as resveratrol
A plant antioxidant used in cosmetic serums.
No specific acne role
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Sodium ascorbyl phosphate · also listed as sodium ascorbyl phosphate, sap
A more stable vitamin C derivative. Derivatives are gentler and more stable, but a pig-skin study found some did not raise skin vitamin C levels the way L-ascorbic acid did.
No specific acne role
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Tetrahexyldecyl ascorbate · also listed as tetrahexyldecyl ascorbate, ascorbyl tetraisopalmitate, thd ascorbate
An oil-soluble vitamin C derivative.
No specific acne role
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Vitamin C (L-ascorbic acid) · also listed as ascorbic acid, l-ascorbic acid, l ascorbic acid, vitamin c, …
The pure form of vitamin C used in antioxidant serums. It is unstable and must be formulated at a low pH (below about 3.5) to get into skin, which is one reason it can sting. It is not an acne treatment.
No specific acne role
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Vitamin E (tocopherol) · also listed as tocopherol, tocopheryl acetate, vitamin e, mixed tocopherols, …
An oil-soluble antioxidant, frequently added to protect oils in a formula from going rancid.
No specific acne role
Soothing ingredient (10)
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Allantoin · also listed as allantoin
A soothing, skin-conditioning ingredient.
Supportive; not an acne treatment
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Aloe vera · also listed as aloe barbadensis leaf juice, aloe barbadensis (aloe vera) leaf juice, aloe vera, aloe barbadensis leaf extract, …
A common soothing base ingredient.
Supportive; not an acne treatment
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Bisabolol · also listed as bisabolol, alpha-bisabolol
A soothing compound originally from chamomile.
Supportive; not an acne treatment
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Centella asiatica · also listed as centella asiatica extract, centella asiatica leaf extract, centella asiatica, cica, …
A plant extract ("cica") used in soothing products. Evidence for acne is limited.
Supportive; not an acne treatment
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Colloidal oatmeal · also listed as colloidal oatmeal, avena sativa kernel flour, avena sativa (oat) kernel flour, oat kernel flour, …
Finely ground oat used as a skin protectant and soothing ingredient.
Supportive; not an acne treatment
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Madecassoside · also listed as madecassoside
A purified compound from Centella asiatica used in soothing products.
Supportive; not an acne treatment
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Niacinamide · also listed as niacinamide, nicotinamide, vitamin b3, nicotinic acid amide
A form of vitamin B3 used for oiliness, redness and barrier support. A 1995 trial found 4% niacinamide gel comparable to 1% clindamycin gel for inflammatory acne, but a 2020 Cochrane review found little high-quality evidence for it, so treat it as a supporting ingredient rather than a primary acne treatment.
Some evidence in acne, limited
Sources: International Journal of Dermatology (1995) : Topical nicotinamide compared with clindamycin gel in the treatment of inflammatory acne vulgaris (opens in a new tab) ; Journal of Cosmetic Dermatology (2004) : Nicotinic acid/niacinamide and the skin (opens in a new tab) ; Cochrane Database of Systematic Reviews (2020) : Topical azelaic acid, salicylic acid, nicotinamide, sulphur, zinc and fruit acid (alpha-hydroxy acid) for acne (opens in a new tab)
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Panthenol · also listed as panthenol, d-panthenol, dexpanthenol, provitamin b5, …
Pro-vitamin B5, a humectant and soothing ingredient common in moisturizers.
Supportive; not an acne treatment
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Zinc gluconate · also listed as zinc gluconate
A zinc salt used in some skin care. Evidence for topical zinc in acne is uncertain.
No specific acne role
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Zinc PCA · also listed as zinc pca
A zinc salt used in products for oily skin. A 2020 Cochrane review was uncertain about the effect of topical zinc in acne.
No specific acne role
Barrier-support lipid (3)
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Ceramides · also listed as ceramide np, ceramide ap, ceramide eop, ceramide ns, …
Skin-identical lipids used in moisturizers to support the skin barrier, which can help if acne treatments make you dry.
Supportive; not an acne treatment
Sources: American Academy of Dermatology : Acne: Diagnosis and treatment (opens in a new tab)
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Cholesterol · also listed as cholesterol
A skin lipid used alongside ceramides in barrier-repair moisturizers.
Supportive; not an acne treatment
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Phytosphingosine · also listed as phytosphingosine
A lipid related to ceramides, used in barrier-support products.
Supportive; not an acne treatment
Humectant (7)
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Butylene glycol · also listed as butylene glycol, 1,3-butylene glycol
A humectant and solvent.
No specific acne role
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Glycerin · also listed as glycerin, glycerine, glycerol
One of the most common and well-tolerated humectants in skin care.
Supportive; not an acne treatment
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Hyaluronic acid · also listed as hyaluronic acid, sodium hyaluronate, hydrolyzed hyaluronic acid, hydrolyzed sodium hyaluronate, …
A humectant that holds water in the top layers of skin. It has no known interaction with acne actives and is often used to offset dryness from retinoids.
Supportive; not an acne treatment
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Propanediol · also listed as propanediol, 1,3-propanediol
A humectant and solvent.
No specific acne role
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Propylene glycol · also listed as propylene glycol
A humectant and solvent. A small number of people are allergic to it.
No specific acne role
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Sodium PCA · also listed as sodium pca
A humectant that is part of the skin's natural moisturizing factor.
Supportive; not an acne treatment
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Urea · also listed as urea
A humectant; at higher strengths it also softens thick, rough skin.
Supportive; not an acne treatment
Emollient, oil or ester (32)
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Acetylated lanolin alcohol · also listed as acetylated lanolin alcohol, acetylated lanolin
A modified lanolin used as an emollient.
Some people with acne choose to limit this
Flagged in rabbit-ear studies: Named by Fulton as a "major offender" in rabbit-ear testing. Rabbit-ear results often overstate what happens on human skin.
Sources: Journal of the Society of Cosmetic Chemists (1989) : Comedogenicity and irritancy of commonly used ingredients in skin care products (opens in a new tab) ; Journal of the American Academy of Dermatology (2006) : A re-evaluation of the comedogenicity concept (opens in a new tab)
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Argan oil · also listed as argan oil, argania spinosa kernel oil
A plant oil used as an emollient.
No specific acne role
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Butyl stearate · also listed as butyl stearate
A fatty ester used in some cosmetics.
Some people with acne choose to limit this
On older comedogenicity lists: Appears on widely shared comedogenicity lists that trace back to rabbit-ear testing of raw ingredients (Fulton, 1980s). We have not verified its individual score against the original paper, and a raw-ingredient score does not tell you how a finished product behaves.
Sources: Journal of the Society of Cosmetic Chemists (1989) : Comedogenicity and irritancy of commonly used ingredients in skin care products (opens in a new tab) ; Journal of the American Academy of Dermatology (2006) : A re-evaluation of the comedogenicity concept (opens in a new tab)
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Caprylic/capric triglyceride · also listed as caprylic/capric triglyceride, caprylic capric triglyceride, fractionated coconut oil
A light emollient made from coconut or palm fatty acids and glycerin.
No specific acne role
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Cetearyl alcohol · also listed as cetearyl alcohol, cetostearyl alcohol, stearyl alcohol
A fatty alcohol (a mix of cetyl and stearyl alcohol) used to thicken creams. It is not a drying alcohol.
No specific acne role
Mixed or low ratings on older lists: Older lists rate fatty alcohols like this low to moderate.
Sources: Journal of the Society of Cosmetic Chemists (1989) : Comedogenicity and irritancy of commonly used ingredients in skin care products (opens in a new tab) ; Journal of the American Academy of Dermatology (2006) : A re-evaluation of the comedogenicity concept (opens in a new tab)
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Cetyl alcohol · also listed as cetyl alcohol
A fatty alcohol used to thicken creams. Despite the name, it is not a drying alcohol.
No specific acne role
Mixed or low ratings on older lists: Older lists rate fatty alcohols like this low to moderate.
Sources: Journal of the Society of Cosmetic Chemists (1989) : Comedogenicity and irritancy of commonly used ingredients in skin care products (opens in a new tab) ; Journal of the American Academy of Dermatology (2006) : A re-evaluation of the comedogenicity concept (opens in a new tab)
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Cocoa butter · also listed as cocoa butter, theobroma cacao seed butter, theobroma cacao (cocoa) seed butter
A rich plant butter.
No specific acne role
Mixed or low ratings on older lists: Often listed as comedogenic on older lists, but a 2007 rabbit-ear study that tested it did not find it comedogenic. The evidence is contradictory.
Sources: Cutaneous and Ocular Toxicology (2007) : Comedogenicity in rabbit: some cosmetic ingredients/vehicles (opens in a new tab) ; Journal of the Society of Cosmetic Chemists (1989) : Comedogenicity and irritancy of commonly used ingredients in skin care products (opens in a new tab)
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Coconut oil · also listed as coconut oil, cocos nucifera oil, cocos nucifera (coconut) oil, virgin coconut oil
A rich plant oil high in lauric acid.
Some people with acne choose to limit this
On older comedogenicity lists: Appears on widely shared comedogenicity lists that trace back to rabbit-ear testing of raw ingredients (Fulton, 1980s). We have not verified its individual score against the original paper, and a raw-ingredient score does not tell you how a finished product behaves.
Sources: Journal of the Society of Cosmetic Chemists (1989) : Comedogenicity and irritancy of commonly used ingredients in skin care products (opens in a new tab) ; Journal of the American Academy of Dermatology (2006) : A re-evaluation of the comedogenicity concept (opens in a new tab)
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Decyl oleate · also listed as decyl oleate
A fatty ester emollient.
Some people with acne choose to limit this
On older comedogenicity lists: Appears on widely shared comedogenicity lists that trace back to rabbit-ear testing of raw ingredients (Fulton, 1980s). We have not verified its individual score against the original paper, and a raw-ingredient score does not tell you how a finished product behaves.
Sources: Journal of the Society of Cosmetic Chemists (1989) : Comedogenicity and irritancy of commonly used ingredients in skin care products (opens in a new tab) ; Journal of the American Academy of Dermatology (2006) : A re-evaluation of the comedogenicity concept (opens in a new tab)
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Dimethicone · also listed as dimethicone, dimethiconol, cyclopentasiloxane, cyclomethicone, …
A silicone that gives a smooth feel and helps reduce water loss. It is common in products labeled for acne-prone skin.
No specific acne role
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Ethylhexyl palmitate (octyl palmitate) · also listed as ethylhexyl palmitate, octyl palmitate, 2-ethylhexyl palmitate
A fatty ester emollient.
Some people with acne choose to limit this
On older comedogenicity lists: Appears on widely shared comedogenicity lists that trace back to rabbit-ear testing of raw ingredients (Fulton, 1980s). We have not verified its individual score against the original paper, and a raw-ingredient score does not tell you how a finished product behaves.
Sources: Journal of the Society of Cosmetic Chemists (1989) : Comedogenicity and irritancy of commonly used ingredients in skin care products (opens in a new tab) ; Journal of the American Academy of Dermatology (2006) : A re-evaluation of the comedogenicity concept (opens in a new tab)
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Ethylhexyl stearate (octyl stearate) · also listed as ethylhexyl stearate, octyl stearate
A fatty ester emollient.
Some people with acne choose to limit this
On older comedogenicity lists: Appears on widely shared comedogenicity lists that trace back to rabbit-ear testing of raw ingredients (Fulton, 1980s). We have not verified its individual score against the original paper, and a raw-ingredient score does not tell you how a finished product behaves.
Sources: Journal of the Society of Cosmetic Chemists (1989) : Comedogenicity and irritancy of commonly used ingredients in skin care products (opens in a new tab) ; Journal of the American Academy of Dermatology (2006) : A re-evaluation of the comedogenicity concept (opens in a new tab)
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Glyceryl stearate · also listed as glyceryl stearate, glyceryl stearate se, peg-100 stearate
An emulsifier used in creams and lotions.
No specific acne role
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Isocetyl stearate · also listed as isocetyl stearate
A fatty ester emollient.
Some people with acne choose to limit this
On older comedogenicity lists: Appears on widely shared comedogenicity lists that trace back to rabbit-ear testing of raw ingredients (Fulton, 1980s). We have not verified its individual score against the original paper, and a raw-ingredient score does not tell you how a finished product behaves.
Sources: Journal of the Society of Cosmetic Chemists (1989) : Comedogenicity and irritancy of commonly used ingredients in skin care products (opens in a new tab) ; Journal of the American Academy of Dermatology (2006) : A re-evaluation of the comedogenicity concept (opens in a new tab)
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Isopropyl isostearate · also listed as isopropyl isostearate
A fatty ester emollient.
Some people with acne choose to limit this
Flagged in rabbit-ear studies: Found comedogenic in a 2007 rabbit-ear study. Human relevance is uncertain.
Sources: Cutaneous and Ocular Toxicology (2007) : Comedogenicity in rabbit: some cosmetic ingredients/vehicles (opens in a new tab) ; Journal of the American Academy of Dermatology (2006) : A re-evaluation of the comedogenicity concept (opens in a new tab)
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Isopropyl myristate · also listed as isopropyl myristate
A fatty ester used to make products feel light and spread easily. It is the textbook example of a comedogenic ingredient in rabbit-ear testing.
Some people with acne choose to limit this
Flagged in rabbit-ear studies: Named by Fulton as a "major offender" in rabbit-ear testing and found comedogenic again in a 2007 rabbit study. Rabbit ears are more sensitive than human skin, and the finished product and concentration matter.
Sources: Journal of the Society of Cosmetic Chemists (1989) : Comedogenicity and irritancy of commonly used ingredients in skin care products (opens in a new tab) ; Cutaneous and Ocular Toxicology (2007) : Comedogenicity in rabbit: some cosmetic ingredients/vehicles (opens in a new tab) ; Journal of the American Academy of Dermatology (2006) : A re-evaluation of the comedogenicity concept (opens in a new tab)
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Isopropyl palmitate · also listed as isopropyl palmitate
A fatty ester closely related to isopropyl myristate.
Some people with acne choose to limit this
Flagged in rabbit-ear studies: Found comedogenic in a 2007 rabbit-ear study. Rabbit-ear results often overstate what happens on human skin.
Sources: Cutaneous and Ocular Toxicology (2007) : Comedogenicity in rabbit: some cosmetic ingredients/vehicles (opens in a new tab) ; Journal of the American Academy of Dermatology (2006) : A re-evaluation of the comedogenicity concept (opens in a new tab)
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Isostearyl neopentanoate · also listed as isostearyl neopentanoate
A fatty ester emollient.
Some people with acne choose to limit this
On older comedogenicity lists: Appears on widely shared comedogenicity lists that trace back to rabbit-ear testing of raw ingredients (Fulton, 1980s). We have not verified its individual score against the original paper, and a raw-ingredient score does not tell you how a finished product behaves.
Sources: Journal of the Society of Cosmetic Chemists (1989) : Comedogenicity and irritancy of commonly used ingredients in skin care products (opens in a new tab) ; Journal of the American Academy of Dermatology (2006) : A re-evaluation of the comedogenicity concept (opens in a new tab)
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Jojoba oil · also listed as jojoba oil, simmondsia chinensis seed oil, simmondsia chinensis (jojoba) seed oil
A liquid plant wax used as a light emollient.
No specific acne role
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Lanolin · also listed as lanolin, lanolin alcohol, lanolin oil, wool wax
A rich emollient from sheep's wool. Some people are allergic to it.
No specific acne role
Mixed or low ratings on older lists: Older lists rate plain lanolin lower than its acetylated forms. Ratings vary.
Sources: Journal of the Society of Cosmetic Chemists (1989) : Comedogenicity and irritancy of commonly used ingredients in skin care products (opens in a new tab) ; Journal of the American Academy of Dermatology (2006) : A re-evaluation of the comedogenicity concept (opens in a new tab)
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Lauric acid · also listed as lauric acid
A medium-chain fatty acid found in coconut oil and used in soaps.
Some people with acne choose to limit this
On older comedogenicity lists: Fulton reported that medium-chain fatty acids were more potent than short- or long-chain ones at producing follicular plugging in rabbit ears. Appears on widely shared comedogenicity lists that trace back to rabbit-ear testing of raw ingredients (Fulton, 1980s). We have not verified its individual score against the original paper, and a raw-ingredient score does not tell you how a finished product behaves.
Sources: Journal of the Society of Cosmetic Chemists (1989) : Comedogenicity and irritancy of commonly used ingredients in skin care products (opens in a new tab) ; Journal of the American Academy of Dermatology (2006) : A re-evaluation of the comedogenicity concept (opens in a new tab)
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Mineral oil · also listed as mineral oil, paraffinum liquidum, liquid paraffin
A refined oil used as an emollient.
No specific acne role
Mixed or low ratings on older lists: Older comedogenicity lists disagree about mineral oil, and ratings depend on the grade tested. Treat any single score with caution.
Sources: Journal of the Society of Cosmetic Chemists (1989) : Comedogenicity and irritancy of commonly used ingredients in skin care products (opens in a new tab) ; Journal of the American Academy of Dermatology (2006) : A re-evaluation of the comedogenicity concept (opens in a new tab)
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Myristic acid · also listed as myristic acid
A medium-chain fatty acid used in cleansers and soaps.
Some people with acne choose to limit this
On older comedogenicity lists: Fulton reported that medium-chain fatty acids were more potent than short- or long-chain ones at producing follicular plugging in rabbit ears. Appears on widely shared comedogenicity lists that trace back to rabbit-ear testing of raw ingredients (Fulton, 1980s). We have not verified its individual score against the original paper, and a raw-ingredient score does not tell you how a finished product behaves.
Sources: Journal of the Society of Cosmetic Chemists (1989) : Comedogenicity and irritancy of commonly used ingredients in skin care products (opens in a new tab) ; Journal of the American Academy of Dermatology (2006) : A re-evaluation of the comedogenicity concept (opens in a new tab)
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Myristyl myristate · also listed as myristyl myristate
A waxy fatty ester used for texture.
Some people with acne choose to limit this
Flagged in rabbit-ear studies: Found comedogenic in a 2007 rabbit-ear study. Human relevance is uncertain.
Sources: Cutaneous and Ocular Toxicology (2007) : Comedogenicity in rabbit: some cosmetic ingredients/vehicles (opens in a new tab) ; Journal of the American Academy of Dermatology (2006) : A re-evaluation of the comedogenicity concept (opens in a new tab)
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Olive oil · also listed as olive oil, olea europaea fruit oil, olea europaea (olive) fruit oil
A plant oil used as an emollient.
No specific acne role
Mixed or low ratings on older lists: Older lists give it a low-to-moderate rating.
Sources: Journal of the Society of Cosmetic Chemists (1989) : Comedogenicity and irritancy of commonly used ingredients in skin care products (opens in a new tab) ; Journal of the American Academy of Dermatology (2006) : A re-evaluation of the comedogenicity concept (opens in a new tab)
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Petrolatum · also listed as petrolatum, petroleum jelly, white petrolatum, vaseline
An occlusive that seals in moisture. Older comedogenicity lists generally rate it low.
No specific acne role
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Rosehip oil · also listed as rosehip oil, rosa canina fruit oil, rosa rubiginosa seed oil
A plant oil used as an emollient.
No specific acne role
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Shea butter · also listed as shea butter, butyrospermum parkii butter, butyrospermum parkii (shea) butter, butyrospermum parkii (shea butter)
A rich plant butter used in moisturizers.
No specific acne role
Mixed or low ratings on older lists: Older lists rate it low to moderate. Heavy butters may feel too rich for oily skin.
Sources: Journal of the Society of Cosmetic Chemists (1989) : Comedogenicity and irritancy of commonly used ingredients in skin care products (opens in a new tab) ; Journal of the American Academy of Dermatology (2006) : A re-evaluation of the comedogenicity concept (opens in a new tab)
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Squalane · also listed as squalane
A lightweight, stable oil (hydrogenated squalene) used as an emollient.
No specific acne role
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Stearic acid · also listed as stearic acid
A long-chain fatty acid used in creams and cleansers.
No specific acne role
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Sunflower seed oil · also listed as sunflower seed oil, helianthus annuus seed oil, helianthus annuus (sunflower) seed oil
A plant oil used as an emollient.
No specific acne role
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Wheat germ oil · also listed as wheat germ oil, triticum vulgare germ oil, triticum vulgare (wheat) germ oil
A plant oil rich in vitamin E.
Some people with acne choose to limit this
On older comedogenicity lists: Appears on widely shared comedogenicity lists that trace back to rabbit-ear testing of raw ingredients (Fulton, 1980s). We have not verified its individual score against the original paper, and a raw-ingredient score does not tell you how a finished product behaves.
Sources: Journal of the Society of Cosmetic Chemists (1989) : Comedogenicity and irritancy of commonly used ingredients in skin care products (opens in a new tab) ; Journal of the American Academy of Dermatology (2006) : A re-evaluation of the comedogenicity concept (opens in a new tab)
Cleansing agent (6)
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Cocamidopropyl betaine · also listed as cocamidopropyl betaine
A mild cleansing agent often used in gentle cleansers.
No specific acne role
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Decyl glucoside · also listed as decyl glucoside, coco-glucoside, lauryl glucoside
A mild, sugar-derived cleansing agent.
No specific acne role
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Laureth-4 · also listed as laureth-4, laureth 4
An emulsifier/surfactant.
Some people with acne choose to limit this
On older comedogenicity lists: Appears on widely shared comedogenicity lists that trace back to rabbit-ear testing of raw ingredients (Fulton, 1980s). We have not verified its individual score against the original paper, and a raw-ingredient score does not tell you how a finished product behaves.
Sources: Journal of the Society of Cosmetic Chemists (1989) : Comedogenicity and irritancy of commonly used ingredients in skin care products (opens in a new tab) ; Journal of the American Academy of Dermatology (2006) : A re-evaluation of the comedogenicity concept (opens in a new tab)
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Sodium cocoyl isethionate · also listed as sodium cocoyl isethionate
A mild cleansing agent used in syndet bars and gentle cleansers.
No specific acne role
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Sodium laureth sulfate · also listed as sodium laureth sulfate, sles
A common cleansing agent, generally milder than sodium lauryl sulfate.
No specific acne role
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Sodium lauryl sulfate · also listed as sodium lauryl sulfate, sls, sodium dodecyl sulfate
A strong cleansing agent that can leave skin tight and irritated, especially alongside retinoids. The tretinoin label advises caution with strongly drying soaps and cleansers.
Some people with acne choose to limit this
On older comedogenicity lists: Appears on widely shared comedogenicity lists that trace back to rabbit-ear testing of raw ingredients (Fulton, 1980s). We have not verified its individual score against the original paper, and a raw-ingredient score does not tell you how a finished product behaves.
Sources: DailyMed, U.S. National Library of Medicine : RETIN-A (tretinoin) cream and gel: label (opens in a new tab) ; Journal of the Society of Cosmetic Chemists (1989) : Comedogenicity and irritancy of commonly used ingredients in skin care products (opens in a new tab) ; Journal of the American Academy of Dermatology (2006) : A re-evaluation of the comedogenicity concept (opens in a new tab)
Fragrance (2)
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Fragrance (parfum) · also listed as fragrance, parfum, perfume, aroma, …
A blend of scent ingredients that does not have to be itemized. Fragrance can irritate or cause allergic reactions in some people, which matters more when retinoids or benzoyl peroxide are already making skin sensitive. Patch testing a new product first can help.
Some people with acne choose to limit this
Sources: American Academy of Dermatology : How to test skin care products (opens in a new tab)
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Labeled fragrance components · also listed as linalool, limonene, d-limonene, geraniol, …
Individual scent chemicals (such as linalool and limonene) that some labels list separately. Their presence means the product is scented.
Some people with acne choose to limit this
Sources: American Academy of Dermatology : How to test skin care products (opens in a new tab)
Potentially drying or irritating (3)
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Denatured alcohol · also listed as alcohol denat, alcohol denat., denatured alcohol, sd alcohol, …
A fast-drying alcohol used in lightweight gels and toners. High amounts can be drying; the tretinoin label advises caution with products high in alcohol.
Some people with acne choose to limit this
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Menthol · also listed as menthol, menthyl lactate
A cooling agent (also in peppermint oil) that can sting sensitized skin.
Some people with acne choose to limit this
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Witch hazel · also listed as witch hazel, hamamelis virginiana water, hamamelis virginiana (witch hazel) water, hamamelis virginiana extract, …
A plant astringent common in toners. The tretinoin label lists astringents among products to use with caution.
Some people with acne choose to limit this
Plant extract or essential oil (9)
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Algae extract · also listed as algae extract, seaweed extract
A general term for seaweed extracts used as skin conditioners.
Some people with acne choose to limit this
On older comedogenicity lists: Appears on widely shared comedogenicity lists that trace back to rabbit-ear testing of raw ingredients (Fulton, 1980s). We have not verified its individual score against the original paper, and a raw-ingredient score does not tell you how a finished product behaves.
Sources: Journal of the Society of Cosmetic Chemists (1989) : Comedogenicity and irritancy of commonly used ingredients in skin care products (opens in a new tab) ; Journal of the American Academy of Dermatology (2006) : A re-evaluation of the comedogenicity concept (opens in a new tab)
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Bakuchiol · also listed as bakuchiol
A plant compound marketed as a retinol alternative. A small 2019 trial found it comparable to retinol for signs of photoaging with less scaling and stinging; it is not an established acne treatment and it is not a retinoid.
No specific acne role
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Citrus peel oils · also listed as lemon peel oil, citrus limon peel oil, citrus limon (lemon) peel oil, orange peel oil, …
Essential oils from lemon, orange, lime or bergamot peel, used for scent.
Some people with acne choose to limit this
Sources: American Academy of Dermatology : How to test skin care products (opens in a new tab)
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Eucalyptus oil · also listed as eucalyptus oil, eucalyptus globulus leaf oil
An essential oil used for scent.
Some people with acne choose to limit this
Sources: American Academy of Dermatology : How to test skin care products (opens in a new tab)
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Green tea extract · also listed as green tea extract, camellia sinensis leaf extract, camellia sinensis (green tea) leaf extract, epigallocatechin gallate, …
A plant extract rich in polyphenol antioxidants, common in products for oily skin.
No specific acne role
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Lavender oil · also listed as lavender oil, lavandula angustifolia oil, lavandula angustifolia (lavender) oil
An essential oil used mainly for scent.
Some people with acne choose to limit this
Sources: American Academy of Dermatology : How to test skin care products (opens in a new tab)
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Peppermint oil · also listed as peppermint oil, mentha piperita oil, mentha piperita (peppermint) oil
An essential oil that contains menthol and can sting.
Some people with acne choose to limit this
Sources: American Academy of Dermatology : How to test skin care products (opens in a new tab)
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Tea tree oil · also listed as tea tree oil, melaleuca alternifolia leaf oil, melaleuca alternifolia (tea tree) leaf oil, melaleuca alternifolia oil, …
An essential oil with some evidence in acne: a 1990 trial found 5% tea tree oil gel reduced lesions but acted more slowly than 5% benzoyl peroxide. Like other essential oils, it can irritate or cause allergy in some people.
Some evidence in acne, limited
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Willow bark extract · also listed as willow bark extract, salix alba bark extract, salix alba (willow) bark extract, salix nigra bark extract, …
A plant extract that contains salicin, a natural relative of salicylic acid. It is not the same as salicylic acid and is not an acne drug; strength varies widely.
No specific acne role
Sunscreen filter (7)
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Avobenzone · also listed as avobenzone, butyl methoxydibenzoylmethane
A chemical UVA filter.
Supportive; not an acne treatment
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Homosalate · also listed as homosalate
A chemical UVB filter.
Supportive; not an acne treatment
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Octinoxate · also listed as octinoxate, ethylhexyl methoxycinnamate, octyl methoxycinnamate
A chemical UVB filter (ethylhexyl methoxycinnamate).
Supportive; not an acne treatment
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Octisalate · also listed as octisalate, ethylhexyl salicylate
A chemical UVB filter (ethylhexyl salicylate). It is a salicylate but not an exfoliant.
Supportive; not an acne treatment
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Octocrylene · also listed as octocrylene
A chemical UV filter.
Supportive; not an acne treatment
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Titanium dioxide · also listed as titanium dioxide, ci 77891
A mineral UV filter, also used as a white pigment in makeup.
Supportive; not an acne treatment
Sources: American Academy of Dermatology : Retinoid or retinol? (opens in a new tab)
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Zinc oxide · also listed as zinc oxide, ci 77947
A mineral UV filter. Daily sunscreen is recommended with retinoids and AHAs.
Supportive; not an acne treatment
Sources: American Academy of Dermatology : Retinoid or retinol? (opens in a new tab) ; U.S. Food and Drug Administration : Alpha hydroxy acids (cosmetic ingredients) (opens in a new tab)
Brightening ingredient (5)
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Alpha arbutin · also listed as alpha-arbutin, alpha arbutin, arbutin
A cosmetic brightening ingredient related to hydroquinone.
No specific acne role
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Hydroquinone · also listed as hydroquinone
A skin-lightening drug used for dark spots. In the US it is no longer legally sold over the counter; the FDA says the only approved hydroquinone product is a prescription cream for melasma. It is not an acne treatment.
No specific acne role · Prescription only in the US (OTC products are not legally marketed)
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Kojic acid · also listed as kojic acid, kojic dipalmitate
A cosmetic brightening ingredient that can irritate some people.
No specific acne role
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Licorice root extract · also listed as licorice root extract, glycyrrhiza glabra root extract, glycyrrhiza glabra (licorice) root extract, dipotassium glycyrrhizate, …
A plant extract used for redness and dark spots.
No specific acne role
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Tranexamic acid · also listed as tranexamic acid
A cosmetic ingredient used for dark spots. It does not treat acne itself.
No specific acne role
Peptide (2)
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Copper peptides · also listed as copper tripeptide-1, copper peptide, copper peptides, ghk-cu
Peptide-copper complexes marketed for skin repair. Evidence is limited.
No specific acne role
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Signal peptides · also listed as palmitoyl pentapeptide-4, palmitoyl tripeptide-1, palmitoyl tetrapeptide-7, acetyl hexapeptide-8, …
Short amino-acid chains marketed for firmness. No known acne interactions.
No specific acne role
Colorant (1)
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D&C Red dyes · also listed as d&c red, d & c red, d and c red, d&c red no. 6, …
Synthetic red colorants used in makeup such as blush and lipstick.
Some people with acne choose to limit this
On older comedogenicity lists: Some older reports flagged D&C red colorants in rabbit-ear testing. Appears on widely shared comedogenicity lists that trace back to rabbit-ear testing of raw ingredients (Fulton, 1980s). We have not verified its individual score against the original paper, and a raw-ingredient score does not tell you how a finished product behaves.
Sources: Journal of the American Academy of Dermatology (1984) : Comedogenicity of current therapeutic products, cosmetics, and ingredients in the rabbit ear (opens in a new tab) ; Journal of the Society of Cosmetic Chemists (1989) : Comedogenicity and irritancy of commonly used ingredients in skin care products (opens in a new tab) ; Journal of the American Academy of Dermatology (2006) : A re-evaluation of the comedogenicity concept (opens in a new tab)
Other (5)
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Caffeine · also listed as caffeine
Used in eye creams and serums. No known acne interactions.
No specific acne role
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Carrageenan · also listed as carrageenan, chondrus crispus extract, chondrus crispus (carrageenan) extract, irish moss extract
A seaweed-derived thickener.
Some people with acne choose to limit this
On older comedogenicity lists: Appears on widely shared comedogenicity lists that trace back to rabbit-ear testing of raw ingredients (Fulton, 1980s). We have not verified its individual score against the original paper, and a raw-ingredient score does not tell you how a finished product behaves.
Sources: Journal of the Society of Cosmetic Chemists (1989) : Comedogenicity and irritancy of commonly used ingredients in skin care products (opens in a new tab) ; Journal of the American Academy of Dermatology (2006) : A re-evaluation of the comedogenicity concept (opens in a new tab)
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Charcoal powder · also listed as charcoal powder, charcoal, activated charcoal
Used in masks and cleansers for oil absorption. It is not an acne drug.
No specific acne role
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Kaolin clay · also listed as kaolin, kaolin clay, bentonite, montmorillonite, …
An oil-absorbing clay used in masks and cleansers. It is not an acne drug.
No specific acne role
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Silica · also listed as silica, hydrated silica, silica dimethyl silylate
A powder used to absorb oil and adjust texture.
No specific acne role
Common formula base ingredient (12)
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Caprylyl glycol · also listed as caprylyl glycol, 1,2-hexanediol, hexanediol, pentylene glycol
A humectant with preservative-boosting properties.
No specific acne role
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Carbomer · also listed as carbomer, acrylates/c10-30 alkyl acrylate crosspolymer, acrylates copolymer, sodium polyacrylate, …
A gelling agent.
No specific acne role
-
Chelating agents · also listed as disodium edta, tetrasodium edta, edta, trisodium ethylenediamine disuccinate, …
Ingredients that bind trace metals to keep a formula stable.
No specific acne role
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Emulsifiers · also listed as polysorbate 20, polysorbate 60, polysorbate 80, ceteareth-20, …
Ingredients that keep oil and water mixed.
No specific acne role
-
Ethylhexylglycerin · also listed as ethylhexylglycerin
A preservative booster and skin conditioner.
No specific acne role
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Film formers and texture agents · also listed as nylon-12, polymethyl methacrylate, methyl methacrylate crosspolymer, polymethylsilsesquioxane, …
Ingredients that adjust feel and finish.
No specific acne role
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pH adjusters · also listed as sodium hydroxide, potassium hydroxide, triethanolamine, tromethamine, …
Small amounts of acids or bases used to set a product's pH.
No specific acne role
-
Phenoxyethanol · also listed as phenoxyethanol
A widely used preservative.
No specific acne role
-
Sodium benzoate · also listed as sodium benzoate, potassium sorbate, benzoic acid, sorbic acid, …
A preservative.
No specific acne role
-
Sodium chloride · also listed as sodium chloride, magnesium sulfate
Salt, used to thicken cleansers.
No specific acne role
-
Water · also listed as water, aqua, eau, water/aqua/eau, …
The usual base (solvent) of creams, gels and serums.
No specific acne role
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Xanthan gum · also listed as xanthan gum, hydroxyethylcellulose, cellulose gum, sclerotium gum, …
A natural thickener.
No specific acne role
Not in the list? That says nothing either way about an ingredient. For common combination questions, see our “Can I use X with Y?” guides.
Key sources 8
- OTC Monograph M006: Topical Acne Drug Products for Over-the-Counter Human Use (opens in a new tab) U.S. Food and Drug Administration , 2021
- Guidelines of care for the management of acne vulgaris (Reynolds et al.) (opens in a new tab) Journal of the American Academy of Dermatology , 2024
- Acne cosmetica (Kligman and Mills) (opens in a new tab) Archives of Dermatology , 1972
- Comedogenicity of current therapeutic products, cosmetics, and ingredients in the rabbit ear (opens in a new tab) Journal of the American Academy of Dermatology , 1984
- Comedogenicity and irritancy of commonly used ingredients in skin care products (opens in a new tab) Journal of the Society of Cosmetic Chemists , 1989
- Comedogenicity in rabbit: some cosmetic ingredients/vehicles (opens in a new tab) Cutaneous and Ocular Toxicology , 2007
- A re-evaluation of the comedogenicity concept (opens in a new tab) Journal of the American Academy of Dermatology , 2006
- Alpha hydroxy acids (cosmetic ingredients) (opens in a new tab) U.S. Food and Drug Administration
Medical review pending. This page was researched and written by the AcneRid Editorial Team from the cited sources, but it has not yet been reviewed by a licensed clinician. We update this notice when a review is complete. About our review process.